Reticulocytes indices in β thalassemia trait individuals
نویسندگان
چکیده
xxx (14.5%). These differences may be explained by the different types of equipment on the market today where the cell measurement methods may be different. Regarding erythrogram and leukogram parameters, the values found for both women and men did not show significant differences compared to values reported in the literature.(1,2,8) Reference values, stratified by gender, are described in Table 1. An important factor to be noted is the characteristic of the population involved in the current study. The Municipal Laboratory receives blood samples from about 100 government healthcare clinics scattered around the city of Curitiba that attend the city's most needy populations. Therefore, our results must be analyzed cautiously to avoid erroneous comparisons. In summary, our results showed that despite the improved technology of cell counting and analysis, the hematological parameters of the adult population of the city of Curitiba suffered no major changes compared to studies performed in the 1980s. However, our work incorporates one new parameter (red cell distribution width), and provides values that better reflect the current conditions of the majority of the adult population of the city of Curitiba, thereby allowing greater accuracy in the interpretation of the data provided by the complete blood count. References
منابع مشابه
Co-inheritance of α-and β-thalassemia: challenges in prenatal diagnosis of thalassemia
Background: The double heterozygous state of α/β thalassemia may alter the hematological indices and modify the phonotype. In addion, definite characterizaon of co-inheritance of α- and β-thalassemia heterozygous carriers may change the process of genec counseling. Materials and Methods: An Iranian couple with low hematological indices was analyzed for α-globin gene deleons using mulpl...
متن کاملThalassemic Mutations in Southern Iran
Background: Approximately 180 mutations have been described in β-thalassemia worldwide with specific spectrum in each ethnic population. This study determines the spectrum and the frequency of β-thalassemia mutations in patients with β-thalassemia trait and sickle cell-β-thalassemia. Methods: Fifteen compound heterozygous sickle cell thalassemia (SCT) and 23 β-thalassemia trait patients were st...
متن کاملThalassemia and Hemoglobin E in Southern Thai Blood Donors
Thalassemia and hemoglobin E (Hb E) are common in Thailand. Individuals with thalassemia trait usually have a normal hemoglobin concentration or mild anemia. Therefore, thalassemic individuals who have minimum acceptable Hb level may be accepted as blood donors. This study was aimed at determining the frequency of α-thalassemia 1 trait, β-thalassemia trait, and Hb E-related syndromes in Souther...
متن کاملPrevalence of renal tubular dysfunction in beta thalassemia minor in shiraz
Background & objective: β-Thalassemia minor is an asymptomatic hereditary disease. The first study on the relation of renal tubular dysfunction and β-thalassemia minor was performed in 2002 but those studies seem inadequate.The main goal of this study is through evaluation of renal tubular function in 100 patients with thalassemia minor. Materials & Methods: 100 patients with β- thalassemia...
متن کاملThe intermediate role of substance use indices in relation between trait impulsivity and emotional dysregulation with state impulsivity in chronic methamphetamine users
Introduction: Impulsivity, which is one of the most important behavioral indicators of addicted people, despite its importance has been studied less frequently. So, regarding the importance of investigating this variable, the present study aimed to investigating the intermediate role of substance use indices in relation between trait impulsivity and emotional dysregulation with state impulsivit...
متن کاملDecreased a Globin mRNA in Nucleated Red Cell Precursors in a Thalassemia
The a thalassemias are associated with a decrease in a chain synthesis. Hemoglobin H (HbH) disease is a moderately severe form of a thalassemia characterized by the production of 5%-20% of HbH, while a thalassemia trait is a milder form of a thalassemia. In two patients with HbH disease, the ratio of a chain synthesis to fi chain synthesis (a/fl ratio) was decreased in both bone marrow cells an...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
عنوان ژورنال:
دوره 33 شماره
صفحات -
تاریخ انتشار 2011